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Hydrocortisone

Cat. No. M3451

All AbMole products are for research use only, cannot be used for human consumption.

Hydrocortisone Structure
Synonym:

Cortisol

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 40  USD40 In stock
100mg USD 30  USD30 In stock
500mg USD 40  USD40 In stock
1g USD 50  USD50 In stock
5g USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland. It is released in response to stress, and to a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis, suppress the immune system, and aid in fat, protein, and carbohydrate metabolism. It also decreases bone formation. Various synthetic forms of cortisol are used to treat a variety of different illnesses.

Product Citations
Customer Product Validations & Biological Datas
Source BMC Ophthalmology. 2020 Nov. Figure 1. hydrocortisone (Abmole Bioscience, USA)
Method proliferation ability assay
Cell Lines HMEC-1 cell
Concentrations 1μg/ml
Incubation Time -
Results Under hyperoxia condition, the proliferation of HMEC-1 is inhibited, 5-40 µM heme promoted the proliferation ability of HMEC-1, more than or equal to 80 µM showed inhibition
Chemical Information
Molecular Weight 362.46
Formula C21H30O5
CAS Number 50-23-7
Solubility (25°C) DMSO 33 mg/mL
Ethanol 10 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Maisam Makarem, et al. PLoS Biol. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells

[2] Catherine Chabot, et al. Mol Cell Biol. New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival

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Keywords: Hydrocortisone, Cortisol supplier, GCR, inhibitors, activators

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