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HP1328 

Cat. No. M29420

All AbMole products are for research use only, cannot be used for human consumption.

HP1328  Structure

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Quality Control & Documentation
Biological Activity

HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia.

Chemical Information
Molecular Weight 389.45
Formula C23H23N3O3
CAS Number 2245074-20-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Tian Tian, et al. J Med Chem. Identification of the Benzoimidazole Compound as a Selective FLT3 Inhibitor by Cell-Based High-Throughput Screening of a Diversity Library

[2] Barbara Waidner, et al. J Bacteriol. Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori

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  Catalog
Abmole Inhibitor Catalog




Keywords: HP1328  supplier, FLT3, inhibitors, activators

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