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HLY78

Cat. No. M14932

All AbMole products are for research use only, cannot be used for human consumption.

HLY78 Structure
Size Price Availability Quantity
1mg USD 45  USD45 In stock
5mg USD 95  USD95 In stock
10mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction.

Chemical Information
Molecular Weight 267.32
Formula C17H17NO2
CAS Number 854847-61-3
Solubility (25°C) DMSO 26 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yanmei Ma, et al. Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer

[2] Xu Luo, et al. HLY78 protects blood-brain barrier integrity through Wnt/β-catenin signaling pathway following subarachnoid hemorrhage in rats

[3] Xu Luo, et al. HLY78 Attenuates Neuronal Apoptosis via the LRP6/GSK3β/β-Catenin Signaling Pathway After Subarachnoid Hemorrhage in Rats

[4] Jing Si, et al. Effects of ionizing radiation and HLY78 on the zebrafish embryonic developmental toxicity

[5] Duozhi Chen, et al. Efficient synthesis of new phenanthridine Wnt/β-catenin signaling pathway agonists

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Keywords: HLY78 supplier, Wnt/beta-catenin, inhibitors, activators

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