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Gigantol

Cat. No. M14931

All AbMole products are for research use only, cannot be used for human consumption.

Gigantol Structure
Size Price Availability Quantity
5mg USD 200  USD200 In stock
10mg USD 320  USD320 In stock
20mg USD 480  USD480 In stock
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Quality Control & Documentation
Biological Activity

Gigantol is a bibenzyl compound derived from several medicinal orchids. Giganto shows promising therapeutic potential against cancer cells. Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.

Chemical Information
Molecular Weight 274.31
CAS Number 67884-30-4
Solubility (25°C) DMSO ≥ 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Audrey Basque, et al. Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig Cells

[2] Yuxing Cai, et al. Gigantol inhibits cell proliferation and induces apoptosis by regulating DEK in non-small cell lung cancer

[3] Yaru Xue, et al. Gigantol ameliorates CCl 4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway

[4] Meili Zhao, et al. Gigantol Attenuates the Metastasis of Human Bladder Cancer Cells, Possibly Through Wnt/EMT Signaling

[5] Nattanan Losuwannarak, et al. Gigantol Targets MYC for Ubiquitin-proteasomal Degradation and Suppresses Lung Cancer Cell Growth

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Keywords: Gigantol supplier, Wnt/beta-catenin, inhibitors, activators

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