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GDC046

Cat. No. M20767

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GDC046 Structure

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Quality Control & Documentation
Biological Activity

GDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4.8 nM, 83.8 nM, 27.6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively.

Chemical Information
Molecular Weight 350.2
Formula C16H13Cl2N3O2
CAS Number 1258292-64-6
Solubility (25°C) DMSO 70 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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  Catalog
Abmole Inhibitor Catalog




Keywords: GDC046 supplier, JAK, inhibitors, activators

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