Gastrin I (rat) TFA is a peptide hormone, which can stimulate gastric acid secretion potently.
| Molecular Weight | 2240.30 |
| Formula | C96H129F3N22O33S2 |
| CAS Number | 81123-06-0 (free base) |
| Form | Solid |
| Solubility (25°C) | Water |
| Storage | Store at ≤ -20°C, protect from light, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Cholecystokinin Receptor Products |
|---|
| Sincalide
Sincalide (Cholecystokinin octapeptide, CCK‐8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. |
| Gastrin I, rat
Gastrin I, rat (Rat Gastrin-17) is a peptide hormone, can stimulate gastric acid secretion potently. |
| Tetragastrin
Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. |
| A71623
A71623, a CCK-4-based peptide, is a potent and highly selective CCK-A full agonist. |
| N-acetyl CCK-(26-30) amide
N-acetyl CCK-(26-30) amide (CCK-(26-30) (sulfated)) is a cholecystokinin (CCK) receptor antagonist. |
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