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Gabapentin HCl

Cat. No. M5669
Gabapentin HCl Structure
Size Price Availability Quantity
10mg USD 63  USD70 In stock
50mg USD 225  USD250 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 207.7
Formula C9H17NO2.HCl
CAS Number 60142-95-2
Purity >98%
Solubility 42 mg/mL in water
Storage at -20°C
References

The role of gabapentin in the management of alcohol withdrawal and dependence.
Leung JG, et al, Ann Pharmacother. 2015 Aug;49(8):897-906. PMID: 25969570.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Gabapentin HCl supplier, GABA Receptor, inhibitors

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