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FT671

Cat. No. M10817

All AbMole products are for research use only, cannot be used for human consumption.

FT671  Structure

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Quality Control & Documentation
Biological Activity

FT671 is a potent, non-covalent, selective USP7 inhibitor,IC50 The value is 52 nM, bound to the USP7 catalytic domain Kd The value is 65 nM.

Chemical Information
Molecular Weight 533.48
Formula C24H23F4N7O3
CAS Number 1959551-26-8
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yiwei Wang, et al. Cell Res. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade

[2] Andrew P Turnbull, et al. Nature. Molecular basis of USP7 inhibition by selective small-molecule inhibitors

[3] Fabricio L Tulini, et al. J Dairy Res. Screening for antimicrobial and proteolytic activities of lactic acid bacteria isolated from cow, buffalo and goat milk and cheeses marketed in the southeast region of Brazil

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  Catalog
Abmole Inhibitor Catalog




Keywords: FT671 supplier, Deubiquitinase, inhibitors, activators

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