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FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively.
| Molecular Weight | 604.49 |
| Formula | C28H42Cl4N6 |
| CAS Number | 1149348-10-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 6 mg/mL (ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C) |
| Storage | 4°C, dry, sealed |
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