Certificate of Analysis
| Product Name: | FGI-106 tetrahydrochloride |
| Catalog Number: | M27848 |
| CAS Number: | 1149348-10-6 |
Physical and Chemical Properties
| Formula: | C28H42Cl4N6 |
| Molecular Weight: | 604.49 |
| Form: | Solid |
| Solubility: | DMSO 6 mg/mL (ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C) |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |