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FCCP

Cat. No. M9051

All AbMole products are for research use only, cannot be used for human consumption.

FCCP Structure
Synonym:

Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone

Size Price Availability Quantity
5mg USD 36  USD36 In stock
10mg USD 52  USD52 In stock
50mg USD 168  USD168 In stock
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Quality Control & Documentation
Biological Activity

FCCP inhibits processing of wild-type APP. FCCP disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation. FCCP (5 μM or 500 nM), baf A1, and NH4Cl induce changes in Tf-Tx and Tf-F cellular fluorescence in K695 cells. FCCP (200 nM) protects and enhances the follicle integrity in cat ovarian tissue during short-term in vitro culture.

Product Citations
Chemical Information
Molecular Weight 254.17
Formula C10H5F3N4O
CAS Number 370-86-5
Form Solid
Solubility (25°C) DMSO: ≥ 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tanpradit N, et al. J Assist Reprod Genet. Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP) pre-exposure ensures follicle integrity during in vitro culture of ovarian tissue but not during cryopreservation in the domestic cat model.

[2] Connop BP, et al. J Neurochem. Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing.

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Keywords: FCCP, Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone supplier, Mitochondrial Related, inhibitors, activators

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