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Eurycomanone

Cat. No. M18283

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Eurycomanone Structure
Synonym:

Tongkat Ali Root Extract

Price and Availability

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Quality Control & Documentation
Biological Activity

Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. Eurycomanone (EN) significantly increased testosterone production dose-dependently at 0.1, 1.0 and 10.0 μM, but the two lower doses when combined with 3-isobutyl-1-methylxanthine (IBMX), the phosphodiesterase inhibitor were not significantly higher than EN or IBMX alone, except at a higher concentration.

Chemical Information
Molecular Weight 354.4
Formula C21H22O5
CAS Number 84633-29-4
Solubility (25°C) DMSO 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xuehua Shao, et al. Ecotoxicol Environ Saf. The botanical eurycomanone is a potent growth regulator of the diamondback moth

[2] Irfan Ahmad Bhat, et al. J Steroid Biochem Mol Biol. Chitosan-eurycomanone nanoformulation acts on steroidogenesis pathway genes to increase the reproduction rate in fish

[3] Norzahirah Ahmad, et al. Pharmaceutics. Bioavailability of Eurycomanone in Its Pure Form and in a Standardised Eurycoma longifolia Water Extract

[4] Nguyen Huu Nhan, et al. Pharm Biol. Production of eurycomanone from cell suspension culture of Eurycoma longifolia

[5] Yusmazura Zakaria, et al. Cancer Cell Int. Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53

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Keywords: Eurycomanone, Tongkat Ali Root Extract supplier, PDE, inhibitors, activators

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