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Erucic acid

Cat. No. M10979
Erucic acid  Structure
Size Price Availability Quantity
100mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Erucic acid is a monounsaturated fatty acid (MUFA) isolated from radish seeds. Erucic acid, which easily crosses the blood-brain barrier (BBB), normalizes the accumulation of long-chain fatty acids in the brain.

Chemical Information
Molecular Weight 338.57
Formula C22H42O2
CAS Number 112-86-7
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Mathilde Kersting, et al. Food Sci Nutr. Erucic acid exposure during the first year of life-Scenarios with precise food-based dietary guidelines

[2] Meric A Altinoz, et al. Mol Aspects Med. PPARδ and its ligand erucic acid may act anti-tumoral, neuroprotective, and myelin protective in neuroblastoma, glioblastoma, and Parkinson's disease

[3] Shaoping Lu, et al. Front Plant Sci. Heterogeneous Distribution of Erucic Acid in Brassica napus Seeds

[4] Vicit Rizal Eh Suk, et al. Curr Drug Deliv. Mixed Oleic Acid-Erucic Acid Liposomes as a Carrier for Anticancer Drugs

[5] Meric A Altinoz, et al. Metab Brain Dis. Erucic acid, a nutritional PPARδ-ligand may influence Huntington's disease pathogenesis

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Keywords: Erucic acid supplier, PI3K, inhibitors, activators

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