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Eribulin mesylate inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin (1-10 nM) induces morphological change and suppresses cell migration in a low concentration in LM8 cells.
In vivo, Eribulin (1 mg/kg; i.v. once a week for 2 weeks) reduces primary tumor growth and lung metastasis of osteosarcoma in mice.
| Molecular Weight | 826.00 |
| Formula | C41H63NO14S |
| CAS Number | 441045-17-6 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, protect from light, sealed |
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