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Elamipretide (MTP-131, SS-31, D-Arg-Dmt-Lys-Phe-NH2) is a cytochrome c peroxidase inhibitor. Elamipretide (MTP-131) is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury. Elamipretide improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice.
| Molecular Weight | 639.79 |
| Formula | C32H49N9O5 |
| CAS Number | 736992-21-5 |
| Solubility (25°C) | Water 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Stuart J Shankland, et al. J Am Soc Nephrol. Podocyte Aging: Why and How Getting Old Matters
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