All AbMole products are for research use only, cannot be used for human consumption.
Elacridar hydrochloride is an inhibitor of P-glycoprotein (P-GP /ABCG1). Blocking p-GP mediated multidrug resistance (MDR) of the cytotoxic compounds doxorubicin and vincristine in CHRC5 cells. It also inhibits breast cancer drug resistance protein (BCRP/ABCG2). Be verbally active.
| Molecular Weight | 600.1 |
| Formula | C34H33N3O5.HCl |
| CAS Number | 143851-98-3 |
| Solubility (25°C) | DMSO 6 mg/mL (May need ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related P-glycoprotein Products |
|---|
| Zosuquidar
Zosuquidar (LY335979) is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). |
| Tariquidar dimesylate
Tariquidar dimesylate (XR9576 dimesylate) is a P-glycoprotein (P-gp) inhibitor. |
| Tariquidar dihydrochloride
Tariquidar dihydrochloride (XR9576 dihydrochloride) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM). |
| Reversin 121
Reversin 121 is a P-glycoprotein inhibitor. |
| Reversin 205
Reversin 205 ([Boc-Glu(Obzl)]2-Lys-Ome) is a P-glycoprotein (ABCB1) inhibitor. |
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