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E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
| Molecular Weight | 530.61 |
| CAS Number | 1225383-33-4 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | 2-8°C, sealed |
[1] Yasmina Filali-Mouncef, et al. The ménage à trois of autophagy, lipid droplets and liver disease
[2] Yifan Chen, et al. Phosphorylation regulates cullin-based ubiquitination in tumorigenesis
[3] Dhanusha A Nalawansha, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine
[4] Ye Xu, et al. Emerging views of mitophagy in immunity and autoimmune diseases
[5] Jun Araya, et al. PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis
| Related Ligand for E3 Ligase Products |
|---|
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