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(E/Z)-Zotiraciclib hydrochloride

Cat. No. M13603
(E/Z)-Zotiraciclib hydrochloride Structure
Synonym:

(E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride

Size Price Availability
5mg USD 110  USD110 Out of stock
10mg USD 150  USD150 Out of stock
50mg USD 450  USD450 Out of stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent CDK2, JAK2, and FLT3 inhibitor.

Chemical Information
Molecular Weight 408.92
CAS Number 1321626-25-8
Solubility (25°C) DMSO 33.33 mg/mL
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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  Catalog
Abmole Inhibitor Catalog




Keywords: (E/Z)-Zotiraciclib hydrochloride, (E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride supplier, CDK, inhibitors, activators


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