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(E)-Ferulic acid

Cat. No. M30259

All AbMole products are for research use only, cannot be used for human consumption.

(E)-Ferulic acid Structure
Synonym:

(E)-Coniferic acid

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Quality Control & Documentation
Biological Activity

(E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.

Chemical Information
Molecular Weight 194.18
Formula C10H10O4
CAS Number 537-98-4
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Veronica F Salau, et al. Fundam Clin Pharmacol. Ferulic acid mitigates diabetic cardiomyopathy via modulation of metabolic abnormalities in cardiac tissues of diabetic rats

[2] Hadley Johnson, et al. J Cosmet Laser Ther. Safety profile of laser-assisted drug delivery of vitamin C, E, and ferulic acid serum following ablative fractional resurfacing: A retrospective chart review

[3] Noriko Shinjyo, et al. J Nat Med. Determination of (E)-ferulic acid content in the root of Angelica acutiloba: a simple chemical evaluation method for crude drug quality control

[4] Xiang Yuan, et al. Nat Prod Res. Phenolics from Lagotis brevituba Maxim

[5] Erin M Burns, et al. PLoS One. Differential effects of topical vitamin E and C E Ferulic® treatments on ultraviolet light B-induced cutaneous tumor development in Skh-1 mice

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Keywords: (E)-Ferulic acid, (E)-Coniferic acid supplier, Wnt/beta-catenin, inhibitors, activators

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