All AbMole products are for research use only, cannot be used for human consumption.
Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
| Molecular Weight | 493.48 |
| CAS Number | 1599440-33-1 |
| Solubility (25°C) | DMSO 7.14 mg/mL |
| Storage | -20°C, sealed |
[2] Peter Sidaway. Nat Rev Clin Oncol. T-DXd effective in HER2-mutant NSCLC
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