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Drotaverine (Drotaverin) is an isoquinoline-based PDE4-selective phosphodiesterase (PDE) inhibitor and an L-type voltage-dependent (voltage-operated) calcium channel (L-VDCC or L-VOCC) blocker that exhibits in vivo antispasmodic efficacy without anticholinergic effects.
| Molecular Weight | 433.97 |
| Formula | C24H31NO4.HCl |
| CAS Number | 985-12-6 |
| Solubility (25°C) | Water 90 mg/mL DMSO 50 mg/mL (ultrasonic and warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] K C Singh, et al. Drotaverine hydrochloride for augmentation of labor
[5] J B Sharma, et al. Drotaverine hydrochloride vs. valethamate bromide in acceleration of labor
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