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Dostarlimab

Cat. No. M24876

All AbMole products are for research use only, cannot be used for human consumption.

Dostarlimab Structure
Synonym:

TSR-042

Size Price Availability
1mg USD 400  USD400 3-4 Weeks
5mg USD 1040  USD1040 3-4 Weeks
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Quality Control & Documentation
Biological Activity

Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively.

Chemical Information
CAS Number 2022215-59-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Mansoor R Mirza, et al. N Engl J Med. Dostarlimab for Primary Advanced or Recurrent Endometrial Cancer

[2] Bárbara Costa, et al. Biomolecules. Dostarlimab: A Review

[3] Ana Oaknin, et al. J Immunother Cancer. Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET-a phase I, singl䲧瘀Ỵ瘁㧀痿

[4] Anthony Markham. Drugs. Dostarlimab: First Approval

[5] No authors listed. Dostarlimab

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  Catalog
Abmole Inhibitor Catalog




Keywords: Dostarlimab, TSR-042 supplier, PD-1/PD-L1, inhibitors, activators

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