Product Name: | Dostarlimab |
Catalog Number: | M24876 |
CAS Number: | 2022215-59-2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
QC Standard: | >95.0% |
H-NMR: | Consistent with structure |
Description: | Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |