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Demethyleneberberine is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates colitis and inhibits inflammation in mice by inhibiting the NF-κB pathway and regulating Th cell balance. Demethyleneberberine can be used as an AMPK activator in the study of non-alcoholic fatty liver disease (NAFLD).
Molecular Weight | 324.35 |
Formula | C19H18NO4+ |
CAS Number | 25459-91-0 |
Storage | 4°C, protect from light, dry, sealed |
[2] Saurabh Gupta, et al. Demethyleneberberine: A possible treatment for Huntington's disease
[5] Kun Wang, et al. The metabolism of berberine and its contribution to the pharmacological effects
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