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Dehydroepiandrosterone is an effective antiapoptotic factor, reversing the serum deprivation-induced apoptosis in prostate cancer cells (DU145 and LNCaP cell lines) as well as in colon cancer cells (Caco2 cell line).
In vivo, DHEA in the diet (0.45 % w/w) of male B6 mice (groups of five mice) treated for 8 weeks led to significant decreases in body temperature compared with mice fed the control AIN-76A diet.
Tissue Cell. 2024 Aug 23;91:102531.
BRD4 absence inactivates endoplasmic reticulum stress to retard dehydroepiandrosterone-triggered ovarian granular cell apoptosis in polycystic ovary syndrome via GRP78
Dehydroepiandrosterone purchased from AbMole
Molecular Weight | 288.42 |
Formula | C19H28O2 |
CAS Number | 53-43-0 |
Solubility (25°C) | Ethanol: 20 mg/mL |
Storage | 10-30°C |
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