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Dehydrocorydaline nitrate

Cat. No. M13531

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Dehydrocorydaline nitrate Structure
Synonym:

13-Methylpalmatine nitrate

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Quality Control & Documentation
Biological Activity

Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities.. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.

Chemical Information
Molecular Weight 428.44
CAS Number 13005-09-9
Storage 2-8°C, protect from light, dry, sealed
References

[1] Motohiro Nonaka, et al. Malar J. Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts

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Keywords: Dehydrocorydaline nitrate, 13-Methylpalmatine nitrate supplier, Bcl-2, inhibitors, activators

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