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Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline chloride elevates p38 MAPK activation. Dehydrocorydaline chloride has anti-inflammatory and anti-cancer activities. Dehydrocorydaline chloride shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.
Molecular Weight | 401.88 |
CAS Number | 10605-03-5 |
Solubility (25°C) | DMSO 25 mg/mL |
Storage | 2-8°C, dry, sealed |
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