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Dacarbazine citrate

Cat. No. M30411

All AbMole products are for research use only, cannot be used for human consumption.

Dacarbazine citrate Structure
Synonym:

Imidazole Carboxamide citrate

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Quality Control & Documentation
Biological Activity

Dacarbazine citrate is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine citrate inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine Citrate can be used for the research of apoptosis and various cancers such as metastatic malignant melanoma.

Chemical Information
Molecular Weight 374.31
Formula C12H18N6O8
CAS Number 64038-56-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Daiki Ueno, et al. Oncotarget. Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy

[2] Ping Liang, et al. Oncotarget. Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells

[3] J M Buesa, et al. Cancer Treat Rep. Phase I trial of intermittent high-dose dacarbazine

[4] G Lunn, et al. Am J Hosp Pharm. Reductive destruction of dacarbazine, procarbazine hydrochloride, isoniazid, and iproniazid

[5] H I Saba, et al. Ann Plast Surg. Adjuvant chemotherapy in malignant melanoma using dacarbazine, carmustine, cisplatin, and tamoxifen: a University of South Florida and H. Lee Moffitt Melanoma Center Study

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Keywords: Dacarbazine citrate, Imidazole Carboxamide citrate supplier, Apoptosis, inhibitors, activators

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