Free shipping on all orders over $ 500

Dacarbazine citrate

Cat. No. M30411

All AbMole products are for research use only, cannot be used for human consumption.

Dacarbazine citrate Structure
Synonym:

Imidazole Carboxamide citrate

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Dacarbazine citrate is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine citrate inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine Citrate can be used for the research of apoptosis and various cancers such as metastatic malignant melanoma.

Chemical Information
Molecular Weight 374.31
Formula C12H18N6O8
CAS Number 64038-56-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Daiki Ueno, et al. Oncotarget. Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy

[2] Ping Liang, et al. Oncotarget. Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells

[3] J M Buesa, et al. Cancer Treat Rep. Phase I trial of intermittent high-dose dacarbazine

[4] G Lunn, et al. Am J Hosp Pharm. Reductive destruction of dacarbazine, procarbazine hydrochloride, isoniazid, and iproniazid

[5] H I Saba, et al. Ann Plast Surg. Adjuvant chemotherapy in malignant melanoma using dacarbazine, carmustine, cisplatin, and tamoxifen: a University of South Florida and H. Lee Moffitt Melanoma Center Study

Related Apoptosis Products
Coenzyme Q0

Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound. Coenzyme Q0 induces apoptosis and autophagy, suppresses of HER-2/AKT/mTOR signaling to potentiate the apoptosis and autophagy mechanisms. Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of inflammation and redox imbalance.

C6 Ceramide

C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway.

DB2115 tertahydrochloride

DB2115 tertahydrochloride is a potent inhibitor of myeloid master regulator PU.1. DB2115 tertahydrochloride has the potential for researching cancers, including hematologic cancers.

14-3-3η Protein inhibitor 1

14-3-3η Protein inhibitor 1 is a 14-3-3η protein inhibitor with a KD of 35 µM.

Deferoxamine

Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.

  Catalog
Abmole Inhibitor Catalog




Keywords: Dacarbazine citrate, Imidazole Carboxamide citrate supplier, Apoptosis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.