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CU-3 

Cat. No. M30717

All AbMole products are for research use only, cannot be used for human consumption.

CU-3  Structure

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Quality Control & Documentation
Biological Activity

CU-3 is the racemate of (5Z,2E)-CU-3. (5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC50 value of 0.6 μM, competitively inhibits the affinity of DGKα for ATP with a Km value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells.

Chemical Information
Molecular Weight 392.47
Formula C16H12N2O4S3
CAS Number 861123-84-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jiawen He, et al. Int J Nanomedicine. Cu3P/1-MT Nanocomposites Potentiated Photothermal-Immunotherapy

[2] Andrea Crovetto, et al. Chem Mater. Is Cu3- x P a Semiconductor, a Metal, or a Semimetal?

[3] Matthew Zervos. Materials (Basel). AACVD of Cu3N on Al2O3 Using CuCl2 and NH3

[4] Patricio Paredes, et al. Nanomaterials (Basel). Surveying the Synthesis, Optical Properties and Photocatalytic Activity of Cu3N Nanomaterials

[5] Mahsa Parvizian, et al. Angew Chem Int Ed Engl. The Chemistry of Cu3 N and Cu3 PdN Nanocrystals

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  Catalog
Abmole Inhibitor Catalog




Keywords: CU-3  supplier, Apoptosis, inhibitors, activators

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