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CP21R7 can inhibitor enhances the induction of KDR+precursors prior to vascular commitment.Cp21R7 compound induced the highest luciferase activity at a concentration of 3 μ M. Immunofluorescence staining revealed that CP21 significantly increased total levels of intracellular -catenin. Activation of WNT signaling via GSK3 inhibition with CP21 induced commitment of hPSCs towards mesoderm.
| Molecular Weight | 317.34 |
| Formula | C19H15N3O2 |
| CAS Number | 125314-13-8 |
| Solubility (25°C) | 63 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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