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CORM-A1

Cat. No. M8288

All AbMole products are for research use only, cannot be used for human consumption.

CORM-A1 Structure

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Quality Control & Documentation
Biological Activity

CORM-A1 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase is an important gaseous signaling mediator in mammalian cells CORM-A1 has anti-oxidant and anti-inflammatory activity.

Chemical Information
Molecular Weight 103.82
Formula CH3BNa2O2
CAS Number 17363-08-5
Solubility (25°C) Water: ≥15 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kapil K Upadhyay, et al. Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function

[2] Cludia Figueiredo-Pereira, et al. Carbon monoxide released by CORM-A1 prevents yeast cell death via autophagy stimulation

[3] Karalyn E McRae, et al. CORM-A1 treatment leads to increased carbon monoxide in pregnant mice

[4] Vance G Nielsen, et al. Comparison of the effects of CORM-2, CORM-3 and CORM-A1 on coagulation in human plasma

[5] Roberto Motterlini, et al. CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule

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