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DSPE-PEG-Streptavidin is an important biocoupling molecule widely used in biomedical research, especially in drug delivery, targeted therapies, immunodiagnostics and biosensors. Through the specific binding between streptavidin and biotin, DSPE-PEG-Streptavidin can help to achieve efficient loading and targeted action in targeted delivery systems. In addition, the molecule is widely used in molecular imaging and bioassays, especially for molecular recognition using the strong affinity between streptavidin and biotin in assay platforms that require high sensitivity and specificity.
DSPE-PEG-Streptavidin has the following properties:
WATER SOLUBILITY: Due to the presence of PEG, DSPE-PEG-Streptavidin has good water solubility and can be stabilised in organisms or in aqueous solutions.
Biocompatibility: PEG has good biocompatibility, which can reduce the immunogenicity of the compound and reduce the toxicity to the organism. Also, Streptavidin has good biocompatibility.
Specific binding: Streptavidin has a high affinity and specific binding ability to bind biotin to form stable complexes.
Chemical modifiability: DSPE-PEG-Streptavidin has a certain degree of hydrophobicity and can form micellar structures or stabilising droplets at the interface. Meanwhile, the hydroxyl group at the end of the PEG chain can be subjected to a variety of chemical modifications to further extend its application.
DSPE-PEG-Streptavidin exhibits multiple uses in bioscience research and applications:
Biosensors: As a key component of biosensors, DSPE-PEG-Streptavidin achieves specific biomolecule recognition and binding ability by modifying on the sensor surface.
Drug Delivery: As a carrier of drug delivery system, DSPE-PEG-Streptavidin can achieve targeted delivery of drugs through its specific binding ability, improving the therapeutic efficacy of drugs and reducing side effects.
Tissue engineering: In the process of constructing artificial tissues and organs, DSPE-PEG-Streptavidin can promote targeted cell growth and tissue regeneration by modifying on the surface of scaffold materials.
Bio-imaging: By modifying on the surface of nanoparticles, DSPE-PEG-Streptavidin can improve the stability and biocompatibility of imaging agents, enabling high-resolution imaging of specific tissues or cells.
Laboratory research: DSPE-PEG-Streptavidin also has a wide range of applications in laboratory research, such as immunoprecipitation, protein purification and protein interaction studies.
Solubility (25°C) | Water |
Storage | -20°C, dry, sealed |
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