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CORM-3

Cat. No. M21403

All AbMole products are for research use only, cannot be used for human consumption.

CORM-3  Structure
Size Price Availability Quantity
20mg USD 115  USD115 In stock
50mg USD 220  USD220 In stock
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Quality Control & Documentation
Biological Activity

CORM-3 is a carbon monoxide-releasing molecule that attenuates nuclear ectopic NF-κB p65, reduces ROS production, and increases intracellular glutathione and superoxide dismutase levels.CORM-3 reduces the activation of NLRP3 inflammatory vesicles.

Chemical Information
Molecular Weight 293.6
Formula C5H3ClNO5Ru
CAS Number 475473-26-8
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chen Jin, et al. Oxid Med Cell Longev. CORM-3 Attenuates Oxidative Stress-Induced Bone Loss via the Nrf2/HO-1 Pathway

[2] Rhiannon F Lyon, et al. Biochem J. CORM-3 induces DNA damage through Ru(II) binding to DNA

[3] Li-Min Zhang, et al. Exp Neurol. CORM-3 exerts a neuroprotective effect in a rodent model of traumatic brain injury via the bidirectional gut-brain interactions

[4] Abdullah Al Mamun, et al. J Adv Res. Role of pyroptosis in spinal cord injury and its therapeutic implications

[5] Kui Lu, et al. Curr Neurovasc Res. CORM-3 Regulates Microglia Activity, Prevents Neuronal Injury, and Improves Memory Function During Radiation-induced Brain Injury

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Keywords: CORM-3 supplier, NF-κB, inhibitors, activators

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