All AbMole products are for research use only, cannot be used for human consumption.
Chloroquine is an inhibitor of autophagy and Toll-like receptors (TLRs). Chloroquine can effectively inhibit SARS-COV-2 infection (EC50=1.13 μM). Chloroquine is an anti-inflammatory widely used in malaria and rheumatoid arthritis.
Autophagy. 2024 Jun 6.
The novel lnc-HZ12 suppresses autophagy degradation of BBC3 by preventing its interactions with HSPA8 to induce trophoblast cell apoptosis
Chloroquine purchased from AbMole
Front Immunol. 2023 Mar 14;14:1120996.
ROS-AMPK/mTOR-dependent enterocyte autophagy is involved in the regulation of Giardia infection-related tight junction protein and nitric oxide levels
Chloroquine purchased from AbMole
Arch Oral Biol. 2023 Apr 18;151:105700.
Wrinkled topography regulates osteogenesis via autophagy-mediated Wnt/β-catenin signaling pathway in MC3T3-E1 cells
Chloroquine purchased from AbMole
Journal of Clinical Hepatology. 2023 Sep;p2103-2109.
Mechanistic studies on the regulation of non-alcoholic fatty liver disease by growth differentiation factor 11
Chloroquine purchased from AbMole
J Clin Hepatol. 2023 Sep;Vol. 39.
Mechanism of growth differentiation factor 11 regulating nonalcoholic fatty liver disease
Chloroquine purchased from AbMole
Ecotoxicol Environ Saf. 2022 Jun 1;237:113564.
Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop
Chloroquine purchased from AbMole
Adv Sci (Weinh). 2021 Feb.
Inhibition Lysosomal Degradation of Clusterin by Protein Kinase D3 Promotes Triple‐Negative Breast Cancer Tumor Growth
Chloroquine purchased from AbMole
Life Sci. 2020 Nov 15;261:118484.
Chloride channel 7 protects from redox status impairment-induced renal tubular epithelial cell apoptosis by activating autophagy
Chloroquine purchased from AbMole
Int J Neurosci. 2020 Mar 11;1-15.
Autophagy-deficiency in Bone Marrow Mononuclear Cells From Patients With Myasthenia Gravis: A Possible Mechanism of Pathogenesis.
Chloroquine purchased from AbMole
Anat Rec (Hoboken). 2020 Jan 21.
Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation
Chloroquine purchased from AbMole
| Molecular Weight | 319.87 |
| Formula | C18H26ClN3 |
| CAS Number | 54-05-7 |
| Solubility (25°C) | DMSO ≥ 50 mg/mL |
| Storage | 4°C, protect from light, sealed |
[2] Winnie Fong, et al. Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy
[4] Bruno Mgarbane. Chloroquine and hydroxychloroquine to treat COVID-19: between hope and caution
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