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CCX354 

Cat. No. M27628

All AbMole products are for research use only, cannot be used for human consumption.

CCX354  Structure

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Quality Control & Documentation
Biological Activity

CCX354 is an antagonist of CCR1, with anti-inflammatory activity.

Chemical Information
Molecular Weight 451.91
Formula C22H22ClN7O2
CAS Number 1010073-75-2
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] A Gilchrist, et al. Br J Pharmacol. Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation and chemotaxis assays

[2] Daniel J Dairaghi, et al. Blood. CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease

[3] Roy Fleischmann. Curr Opin Rheumatol. Novel small-molecular therapeutics for rheumatoid arthritis

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  Catalog
Abmole Inhibitor Catalog




Keywords: CCX354  supplier, CCR, inhibitors, activators

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