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CCT373566 

Cat. No. M29579

All AbMole products are for research use only, cannot be used for human consumption.

CCT373566  Structure

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Quality Control & Documentation
Biological Activity

CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo.

Chemical Information
Molecular Weight 547
Formula C26H29ClF2N6O3
CAS Number 2378853-66-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Alice C Harnden, et al. J Med Chem. Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones

[2] Rosemary Huckvale, et al. J Med Chem. Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo

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  Catalog
Abmole Inhibitor Catalog




Keywords: CCT373566  supplier, Bcl-2, inhibitors, activators

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