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CCR7 Ligand 1 (CCR7-Cmp2105) is a human CC chemokine receptor 7 (CCR7) variant ligand and a potent intracellular CCR7 receptor variant antagonist with a Kd value of 3 nM. In addition, CCR7 Ligand 1 also inhibited CCL19 activation with an IC50 value of 7.3 μM.
| Molecular Weight | 475.56 |
| Formula | C22H29N5O5S |
| CAS Number | 681514-83-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | -20°C |
[3] Hiroyuki Tsuchiya et al. Regen Ther. Immune evasion by cancer stem cells
[4] Anwar Salem et al. Biochim Biophys Acta Rev Cancer. CCR7 as a therapeutic target in Cancer
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