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Cafestol

Cat. No. M19411

All AbMole products are for research use only, cannot be used for human consumption.

Cafestol Structure
Size Price Availability Quantity
1mg USD 30  USD30 In stock
5mg USD 65  USD65 In stock
10mg USD 105  USD105 In stock
20mg USD 170  USD170 In stock
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Quality Control & Documentation
Biological Activity

Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activatio䲧瓰Ỵ瓱��㧀

Chemical Information
Molecular Weight 316.43
Formula C20H28O3
CAS Number 469-83-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage 4°C, protect from light
References

[1] Ju-Chi Liu, et al. Evid Based Complement Alternat Med. Cafestol Inhibits High-Glucose-Induced Cardiac Fibrosis in Cardiac Fibroblasts and Type 1-Like Diabetic Rats

[2] Rob M van Dam, et al. N Engl J Med. Coffee, Caffeine, and Health

[3] Renalison Farias-Pereira, et al. Food Chem. Cafestol increases fat oxidation and energy expenditure in Caenorhabditis elegans via DAF-12-dependent pathway

[4] Yaqi Ren, et al. Int J Mol Sci. Cafestol and Kahweol: A Review on Their Bioactivities and Pharmacological Properties

[5] Masood Sadiq Butt, et al. Crit Rev Food Sci Nutr. Coffee and its consumption: benefits and risks

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Keywords: Cafestol supplier, ERK, inhibitors, activators

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