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BRD6688 

Cat. No. M28352

All AbMole products are for research use only, cannot be used for human consumption.

BRD6688  Structure

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Quality Control & Documentation
Biological Activity

BRD6688 is a selective HDAC2 inhibitor. BRD6688 increases H4K12 and H3K9 histone acetylation in primary mouse neuronal cells. BRD6688 crosses the blood brain barrier and rescues the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model.

Chemical Information
Molecular Weight 282.34
Formula C16H18N4O
CAS Number 1404562-17-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Xiao-Min Wang, et al. Mol Cancer Ther. Dysregulation of EAAT2 and VGLUT2 Spinal Glutamate Transports via Histone Deacetylase 2 (HDAC2) Contributes to Paclitaxel-induced Painful Neuropathy

[2] F F Wagner, et al. Chem Sci. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers

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  Catalog
Abmole Inhibitor Catalog




Keywords: BRD6688  supplier, HDAC, inhibitors, activators

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