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Borussertib

Cat. No. M20677

All AbMole products are for research use only, cannot be used for human consumption.

Borussertib Structure
Size Price Availability Quantity
5mg USD 330  USD330 In stock
10mg USD 500  USD500 In stock
25mg USD 900  USD900 In stock
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Quality Control & Documentation
Biological Activity

Borussertib is a first-in-class covalently-mutated inhibitor of the protein kinase Akt, with an IC50 value of 0.8 nM and a Ki value of 2.2 nM for Aktwt.

Chemical Information
Molecular Weight 596.68
Formula C36H32N6O3
CAS Number 1800070-77-2
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jrn Weisner, et al. Cancer Res. Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer

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  Catalog
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Keywords: Borussertib supplier, Akt, inhibitors, activators

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