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Bomedemstat (IMG-7289) is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. Bomedemstat can increase H3K4 and H3K9 methylation, and then alter gene expression. Bomedemstat shows anti-cancer activities, inhibits cancer cell proliferation and induces apoptosis.
| Molecular Weight | 519.61 |
| Formula | C28H34FN7O2 |
| CAS Number | 1990504-34-1 |
| Form | Oil |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Douglas Tremblay, et al. Cells. Next Generation Therapeutics for the Treatment of Myelofibrosis
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Products are for research use only. Not for human use. We do not sell to patients.
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