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BML-284 (Wnt agonist 1) is a potent and selective activator of Wnt signaling. BML-284 enhances beta-catenin and increases transcript and protein levels of p-gp. BML-284 increases the migration and invasion of both MNK45 and AGS cells and partially restores the migratory and invasive abilities of cells inhibited by pizotifen. BML-284 induces the expression of β-catenin significantly when compared with the NC group.
Neurochem Res. 2023 Feb 24.
Analgesic effect of perineural injection of BoNT/A on neuropathic pain induced by chronic constriction injury of sciatic nerve in rats
BML-284 purchased from AbMole
| Molecular Weight | 350.37 |
| Formula | C19H18N4O3 |
| CAS Number | 853220-52-7 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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