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Bilobetin

Cat. No. M16793

All AbMole products are for research use only, cannot be used for human consumption.

Bilobetin Structure
Size Price Availability Quantity
1mg USD 50  USD50 In stock
5mg USD 180  USD180 In stock
10mg USD 320  USD320 In stock
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Biological Activity

Bilobetin is a biflavonoid extracted from Ginkgo biloba with a variety of biological functions. Bilobetin has significant antioxidant activity, scavenging free radicals and reducing cellular damage from oxidative stress. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity.

Chemical Information
Molecular Weight 552.48
Formula C31H20O10
CAS Number 521-32-4
Solubility (25°C) DMSO 110 mg/mL
Storage 4°C, protect from light
References

[1] Cong Wang, et al. Ann Dermatol. Inhibition of Insulin-Like Growth Factor-1-Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

[2] Jinrui Zhang, et al. Nat Prod Res. Bilobetin, a novel small molecule inhibitor targeting influenza virus polymerase acidic (PA) endonuclease was screened from plant extracts

[3] Xue Feng, et al. J Sep Sci. Identification of bilobetin metabolites, in vivo and in vitro, based on an efficient ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry strategy

[4] Heebin Son, et al. Biomed Chromatogr. Quantitative determination of bilobetin in rat plasma by HPLC-MS/MS and its application to a pharmacokinetic study

[5] Qun Wang, et al. Phytomedicine. Bilobetin induces kidney injury by influencing cGMP-mediated AQP-2 trafficking and podocyte cell cycle arrest

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Keywords: Bilobetin supplier, Flavonoids, inhibitors, activators

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