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BI-6C9 is a highly specific BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potential (MOMP) and mitochondrial fission, and protects the cells from mitochondrial apoptosis inducing factor (AIF) release and caspase-independent cell death in neurons.
| Molecular Weight | 471.59 |
| Formula | C23H25N3O4S2 |
| CAS Number | 791835-21-7 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] L Hinder, et al. Characterization of Novel Diphenylamine Compounds as Ferroptosis Inhibitors
[2] Anja Jelinek, et al. Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis
[3] Sandra Neitemeier, et al. BID links ferroptosis to mitochondrial cell death pathways
[4] O Cooley-Andrade, et al. Detergent Sclerosants Stimulate Leukocyte Apoptosis and Oncosis
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