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BETd-260 (ZBC 260) is a PROTAC connected by the Cereblon ligand and bet ligands in leukemia cells RS4; 11 At low concentrations of 30 pM, BRD4 protein activity is reduced. BETd-260 significantly inhibits the activity of HCC cells in hepatocellular carcinoma and induces apoptosis.
| Molecular Weight | 798.89 |
| Formula | C43H46N10O6 |
| CAS Number | 2093388-62-4 |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage | -80°C, protect from light, dry, sealed |
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