Certificate of Analysis
| Product Name: | BETd-260 |
| Catalog Number: | M10793 |
| CAS Number: | 2093388-62-4 |
Physical and Chemical Properties
| Formula: | C43H46N10O6 |
| Molecular Weight: | 798.89 |
| Solubility: | DMSO ≥ 20 mg/mL |
| Storage: | -80°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BETd-260 (ZBC 260) is a PROTAC connected by the Cereblon ligand and bet ligands in leukemia cells RS4; 11 At low concentrations of 30 pM, BRD4 protein activity is reduced. BETd-260 significantly inhibits the activity of HCC cells in hepatocellular carcinoma and induces apoptosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |