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Indisulam is a carbonic anhydrase inibitor and antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition.
| Molecular Weight | 385.85 |
| Formula | C14H12ClN3O4S2 |
| CAS Number | 165668-41-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | Powder -20°C |
[2] Claudiu T Supuran. Indisulam: an anticancer sulfonamide in clinical development
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