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BAY-218

Cat. No. M20651

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BAY-218 Structure

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Quality Control & Documentation
Biological Activity

BAY-218 is a potent and selective small-molecule AhR inhibitor, inhibiting AhR nuclear translocation, dioxin response element (DRE)-luciferase reporter expression and AhR-regulated target gene expression induced by both exogenous and endogenous AhR ligands.

Chemical Information
Molecular Weight 401.82
Formula C20H17ClFN3O3
CAS Number 2162982-11-6
Solubility (25°C) DMSO 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuting Chen, et al. Toxicol Lett. Human CYP1B1 enzyme-mediated, AhR enhanced activation of aflatoxin B1 for its genotoxicity in human cells

[2] Zongying Yang, et al. Toxicology. Influence of aryl hydrocarbon receptor and sulfotransferase 1A1 on bisphenol AF-induced clastogenesis in human hepatoma cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: BAY-218 supplier, Aryl hydrocarbon Receptor, inhibitors, activators

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