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AZD2098

Cat. No. M13921

All AbMole products are for research use only, cannot be used for human consumption.

AZD2098 Structure
Size Price Availability Quantity
5mg USD 80  USD80 In stock
10mg USD 140  USD140 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.

Chemical Information
Molecular Weight 334.18
CAS Number 566203-88-1
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nicholas Kindon, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists

[2] No authors listed. Charity gives life to languishing drugs

[3] Anke Zhang, et al. CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats

[4] Anthony J DeSantis, et al. Chemokine receptor antagonists with α 1-adrenergic receptor blocker activity

[5] Fang Liu, et al. Hyperoside inhibits proinflammatory cytokines in human lung epithelial cells infected with Mycoplasma pneumoniae

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Keywords: AZD2098 supplier, CCR, inhibitors, activators

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