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AZ084

Cat. No. M13920

All AbMole products are for research use only, cannot be used for human consumption.

AZ084 Structure
Size Price Availability Quantity
1mg USD 160  USD160 In stock
5mg USD 350  USD350 In stock
10mg USD 540  USD540 In stock
25mg USD 870  USD870 In stock
50mg USD 1460  USD1460 In stock
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Quality Control & Documentation
Biological Activity

AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma.

Chemical Information
Molecular Weight 434.57
CAS Number 929300-19-6
Solubility (25°C) DMSO 150 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ming Wang, et al. Tumor-derived exosomes drive pre-metastatic niche formation in lung via modulating CCL1 + fibroblast and CCR8 + Treg cell interactions

[2] Stephen Connolly, et al. Orally bioavailable allosteric CCR8 antagonists inhibit dendritic cell, T cell and eosinophil migration

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Keywords: AZ084 supplier, CCR, inhibitors, activators

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